In this paper I examine which is the most appropriate moral theory for dealing with disaster bioethics contexts. It is pointed out that, contrary to what is usually believed, moral theories of right action cannot actually guide us in such difficult situations. Instead, it is claimed that a virtue ethics theory of an Aristotelian version, which gives emphasis not only on the virtuous person but also on the relevant developmental process of becoming virtuous, can provide us with the right theoretical (...) framework for coping with the problems which the victims of such disastrous situations face. (shrink)

Participants in this study were ethnic Hungarian secondary students attending high schools in Romania in which Hungarian was the primary language of instruction. Attitudes of participants toward ethnic and cultural groups were measured using a variation of the Bogardus (1933) Scale of Social Distance. Results were consistent with predictions based on Allport's intergroup contact theory. Students reported a wide range of tolerance levels for majority and minority ethnic groups with which they were likely to have contact in Romania. However, the (...) students reported little difference in tolerance levels for groups that are not a recognized part of the Romanian cultural landscape, such as people of Hispanic origin, and Native Americans. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

My aim in this paper is to attempt a philosophical reading of M. Karagatsis’ novel Kitrinos Fakelos (1956), focusing my analysis on the passions and the emotions of its fictional characters, aiming at demonstrating their independence as well as the presentation of their psychography in Karagatsis’ novel where the description of the emotions caused by love is a dominant feature. In particular, I will examine the expression of desire, love (erôs) and sympathy in this novel – passions and emotions that (...) play an important role to moral life and human existence in general. I will be approaching these issues from the point of view of moral philosophy, analyzing the passions and the emotions expressed by the fictional characters in Kitrinos Fakelos, and in particular of the fictional character of Manos Tasakos. At the same time, I will attempt to show the philosophical influences that M. Karagatsis has received in his literary work, and especially in his novel Kitrinos Fakelos, by the philosophical thought of Friedrich Nietzsche. In addition, I will try to demonstrate the contrast between the Nietzschean moral model and that of both ancient and contemporary virtue ethical theory, in relation to the traditional interpretation of the work of Nietzsche’s that Karagatsis adopts, along with many of his contemporaries in Greece from the beginning of the 20th century until the 70’s at least. (shrink)

(2012). Speusippus on Cognitive Sense Perception: Sextus Empiricus M 7.145‐6. British Journal for the History of Philosophy: Vol. 20, No. 6, pp. 1183-1193. doi: 10.1080/09608788.2012.731246.

Transcranial direct current stimulation over the contralateral primary motor cortex of the target muscle has been described to enhance corticospinal excitability, as measured with transcranial magnetic stimulation. Recently, tDCS targeting the brain regions functionally connected to the contralateral primary motor cortex was reported to enhance corticospinal excitability more than conventional tDCS. We compared the effects of motor network tDCS, 2 mA conventional tDCS, and sham tDCS on corticospinal excitability in 21 healthy participants in a randomized, single-blind within-subject study design. We (...) applied tDCS for 12 min and measured corticospinal excitability with TMS before tDCS and at 0, 15, 30, 45, and 60 min after tDCS. Statistical analysis showed that neither motor network tDCS nor conventional tDCS significantly increased corticospinal excitability relative to sham stimulation. Furthermore, the results did not provide evidence for superiority of motor network tDCS over conventional tDCS. Motor network tDCS seems equally susceptible to the sources of intersubject and intrasubject variability previously observed in response to conventional tDCS. (shrink)

Lorsque la revue m’a proposé de rédiger le compte-rendu du livre collectif coordonné par Isabelle Clair et Elsa Dorlin, j’ai tout de suite accepté. La rencontre avec Eleni Varikas a été pour moi l’une des plus belles expériences que j’ai pu vivre dans le monde universitaire. L’œuvre d’Eleni m’a particulièrement marquée et ses écrits sont au programme de mes cours de théorie politique et d’histoire des idées politiques dans une perspective féministe depuis de nombreuses années. Non seulement s...

The use of placebo in clinical practice has been the topic of extensive debate in the bioethics literature, with much scholarship focusing on concerns regarding deception. While considerations of placebo without deception have largely centred on open-label placebo, this paper considers a different kind of ethical quandary regarding placebo without an intent to deceive—one where the provider believes a treatment is effective due to a direct physiological mechanism, even though that belief may not be supported by rigorous scientific evidence. This (...) is often the case with complementary and alternative medicine (CAM) techniques and also with some mainstream therapies that have not proven to be better than sham. Using one such CAM technique as a case study—electroencephalography (EEG) neurofeedback for attention-deficit/hyperactivity disorder (ADHD)—this paper explores the ethics of providing therapies that may have some beneficial effect, although one that is likely due to placebo effect. First, we provide background on EEG neurofeedback for ADHD and its evidence base, showing how it has proven to be equivalent to—but not better than—sham neurofeedback. Subsequently, we explore whether offering therapies that are claimed to work via specific physical pathways, but may actually work due to the placebo effect, constitute deception. We suggest that this practice may constitute unintentional deception regarding mechanism of action. Ultimately, we argue that providers have increased information provision obligations when offering treatments that diverge from standard of care and we make recommendations for mitigating unintentional deception. (shrink)

While downsizing has been widely studied, its connection to firm ownership status and the reasons behind it are missing from extant research. We explore the relationship between downsizing and family ownership status among Fortune 500 firms. We␣propose that family firms downsize less than non-family firms, irrespective of performance, because their relationship with employees is based on normative commitments rather than financial performance alone. We suggest that their actions are related to employee- and community-friendly policies. We find that family businesses do (...) downsize less irrespective of financial performance considerations. However, their actions are not related to their employee- or community-friendly practices. The results raise issues related to the motivations of large multinationals to␣downsize and the drivers of their stakeholder management practices. (shrink)

Abstract In this paper, we show that Greek distinguishes empirically ability as a precondition for action, and ability as initiating and sustaining force for action. In this latter case, the ability verb behaves like an action verb, and the sentence has the logical form of a causative structure φ CAUSE [BECOME ψ] (Dowty 1979). The distinction between ability as potential for action and ability as action itself has a venerable tradition that goes back to Aristotle, and is recently implied in (...) a number of analyses (Mari and Martin 2007, 2009, Thomason 2005). We show first that the phenomenon is not just aspectual ( pace Bhatt 1999, Hacquard 2006, 2009, Pinon 2003): actualized ability emerges with the ability verb also with imperfective aspect and present tense. They key, we argue is causation, which triggers a shift from pure ability, to ability as force (in the sense of Copley and Harley 2010, i.e. as action initiating energy). In Greek, the action reading of the ability modal comes about in an apparent co-ordinate causative structure, where the two clauses are connected with conjunction ke ‘and’— a pattern that we find also in other languages, including English, at least with some action verbs such as try, allow . Our analysis implies a meaning of ability richer than mere possibility ( pace Hacquard); and, by capitalizing on the causative meaning and the presence of force in causative structures, our analysis enables a principled explanation of the shift to action-ability without positing ambiguity for the ability verb ( pace Bhatt 1999). (shrink)

Marina Gustavovna Shtorkh is a daughter of Gustav Shpet (1879-1937), one of the most important Russian philosophers of the 20th century. He spent the last two years of his life (1935-1937) in exile in Siberia. M.G. Shtorkh shares her memories in a documentary film about her father and his circle, the intellectual leaders of the Silver Age, philosophers, actors, artists: A. Belyi, V. Kachalov, I. Moskvin, A. Shchusev, B. Pil`niak, etc. This book by Elena Iakovich is a transcript of the (...) film. (shrink)

This book contributes to the 'rehabilitation' of Plutarch as a philosopher by focusing on an important aspect of his philosophical self: his work as a teacher, interpreter, and, eventually, historian of philosophy.

Neurotherapies for diagnostics and treatment—such as electroencephalography (EEG) neurofeedback, single-photon emission computerized tomography (SPECT) imaging for neuropsychiatric evaluation, and off-label/experimental uses of brain stimulation—are continuously being offered to the public outside mainstream healthcare settings. Because these neurotherapies share many key features of complementary and alternative medicine (CAM) techniques—and meet the definition of CAM as set out in Kaptchuk and Eisenberg—here we refer to them as “alternative neurotherapies.” By explicitly linking these alternative neurotherapy practices under a common conceptual framework, this paper (...) draws attention to, and critically considers, the cross-cutting ethical and legal issues related to the provision of these services. The first section of this paper provides an updated empirical overview of uses of SPECT neuropsychiatric evaluations, EEG neurofeedback, and experimental/off-label forms of brain stimulation. Next, drawing on CAM bioethics scholarship, we highlight the pertinent ethical issues in the alternative neurotherapy context, including the truthful representation of evidence base, marketing to vulnerable populations, potential harms, provider competency, and conflicts of interest. Finally, we consider the principal legal issues at stake for the provision of alternative neurotherapies in the U.S., namely those related to licensing and scope-of-practice considerations. We conclude with recommendations for future research in this domain. (shrink)

Direct-to-consumer (DTC) genetic tests (GT) enable consumers to access a wide range of GT, without involving a healthcare professional, promoting an increasing disassociation of genetics from the clinical context. This study explores, through semi-structured interviews, the experiences and attitudes of European clinical geneticists towards DTCGT. Our results indicate that the participants have limited experience of consultations with patients regarding such tests. The majority of participants stated that consumers purchased tests out of curiosity and sought a general interpretation of test results (...) by a healthcare professional. Most respondents were skeptical of the quality of tests, especially regarding their clinical utility. The participants supported the importance of medical supervision and genetic counseling in this context. Finally, most respondents considered it their duty to accept consultations concerning DTCGT results. However, due to concerns over limited time and potential downstream costs, some participants supported that a prioritization system based on guidelines would be necessary. (shrink)

Name der Zeitschrift: Semiotica Jahrgang: 2017 Heft: 214 Seiten: 307-329.

This paper considers different subjective measures of conscious and unconscious knowledge in a concept formation paradigm. In particular, free verbal reports are compared with two subjective measures, the zero-correlation and the guessing criteria, based on trial-by-trial confidence ratings (a type of on-line verbal report). Despite the fact that free verbal reports are frequently dismissed as being insensitive measures of conscious knowledge, a considerable bulk of research on implicit learning has traditionally relied on this measure of consciousness, because it is widely (...) regarded as almost self-evident that the content of any conscious state that is intentional and conceptual can be expressed verbally. However, we found that the most recently developed subjective measures based on trial-by-trial confidence ratings provided a more sensitive measure of conscious and unconscious knowledge than free verbal reports. In a complementary way, the qualitative pattern of the free report and the confidence measures were similar, providing further evidence for the validity of the latter. (shrink)

Electroencephalography (EEG) neurofeedback is a type of biofeedback that purportedly teaches users how to control their brainwaves. Although neurofeedback is currently offered by thousands of providers worldwide, its provision is contested, as its effectiveness beyond a placebo effect is unproven. While scholars have voiced numerous ethical concerns about neurofeedback—regarding opportunity cost, physical and psychological harms, financial cost, and informed consent—to date these concerns have remained theoretical. This pilot study aimed to provide insights on whether these issues were supported by empirical (...) data from the experiences of neurofeedback users. Semi-structured telephone interviews were conducted with individuals who had used EEG neurofeedback for themselves and/or for a child. The majority of respondents (N = 36) were female (75%), white (92%), and of higher socioeconomic status relative to the U.S. population. Among adult users (n = 33), most (78.8%) resorted to neurofeedback after having tried other therapies, and were satisfied with the treatment (81.8%). The majority paid for neurofeedback out-of-pocket (72.7%) and considered it to be good value for money (84.8%). More than half (57.6%) considered neurofeedback to be a scientifically well-established therapy. However, of those, 78.9% were using neurofeedback for indications not adequately supported by scientific evidence. Concerns regarding opportunity cost, physical and psychological harms, and financial cost are not substantiated by our findings. Our results partially support concerns regarding insufficient understanding of limitations. This study underlines the disconnect between some of the theoretical concerns raised by scholars regarding the use of non-validated therapies and the lived experiences of users. (shrink)

This collection addresses a post-WWII shift in the hierarchy of scientific explanations, where the highest goal moves from reductionism towards some ...

My aim in this paper is to demonstrate the relevance of the Aristotelian notion of civic friendship to contemporary political discussion by arguing that it can function as a social good. Contrary to some dominant interpretations of the ancient conception of friendship according to which it can only be understood as an obligatory reciprocity, I argue that friendship between fellow citizens is important because it contributes to the unity of both state and community by transmitting feelings of intimacy and solidarity. (...) In that sense, it can be understood as an important relationship predicated on affection and generosity, virtues lacking from both contemporary politics and society that seem to be merely dominated by Post-Enlightenment ideals. For Aristotle, friendship is important for society because it generates concord, articulating thus a basis for social unity and political agreement. (shrink)

In this paper we suggest that there is a need to examine what is meant by “context” in Social Psychology and present an example of how to place identity in its social and institutional context. Taking the case of British naturalisation, the process whereby migrants become citizens, we show that the identity of naturalised citizens is defined by common-sense ideas about Britishness and by immigration policies. An analysis of policy documents on “earned citizenship” and interviews with naturalised citizens shows that (...) the distinction between “elite” and “non-elite” migrants is evident in both the “reified” sphere of policy and the “common sense” sphere of everyday identity construction. While social representations embedded in lay experience construct ethno-cultural similarity and difference, immigration policies engage in an institutionalised positioning process by determining migrants' rights of mobility. These spheres of knowledge and practice are not disconnected as these two levels of “managing otherness” overlap—it is the poorer, less skilled migrants, originating outside the West who epitomise difference (within a consensual sphere) and have less freedom of mobility (within a reified sphere). We show that the context of identity should be understood as simultaneously psychological and political. (shrink)

The book in front of you is the first international academic volume on the legal, philosophical and economic aspects of the rise of 3D printing. In recent years 3D printing has become a hot topic. Some claim that it will revolutionize production and mass consumption, enabling consumers to print anything from clothing, automobile parts and guns to various foods, medication and spare parts for their home appliances. This may significantly reduce our environmental footprint, but also offers potential for innovation and (...) creativity. At the same time 3D printing raises social, ethical, regulatory and legal questions. If individuals can print anything they want, how does this affect existing systems of intellectual property rights? What are the societal consequences of the various types of products one can print with a 3D printer, for example weapons? Should all aspects of 3D printing be regulated, and if so, how and to what ends? How will businesses (have to) change their way of working and their revenue model in light of the shift to printing-on-demand? How will the role of product designers change in a world where everyone has the potential to design their own products? These and other questions are addressed in high quality and in-depth contributions by academics and experts, bringing together a wide variety of academic discussions on 3D printing from different disciplines as well as presenting new views, broadening the discussion beyond the merely technical dimension of 3D printing. Bibi van den Berg is Associate Professor at eLaw, the Center for Law and Digital Technologies at Leiden University, The Netherlands. Simone van der Hof is Full Professor at eLaw in Leiden and Eleni Kosta is Associate Professor at TILT, the Tilburg Institute for Law, Technology and Society at Tilburg University, The Netherlands. (shrink)

The concept of ?ethical consumer behavior? has gained significant attention among practitioners and academic researchers, generating increasing but disjointed knowledge on the topic. By analyzing the empirical research on ethical consumer behavior, this article provides researchers with a map to guide future research. In total, we review 80 studies. The main contributions of the article include the identification of the main trends in the ethical consumer literature and the conceptualization of ethical consumer behavior. In addition, several areas for future research (...) are proposed and discussed. (shrink)

Shared Content as Speaker Meaning Cappelen and Lepore have recently emphasised the significance of a minimal notion of perfectly shared content for pragmatic theories. This paper argues for a similar notion, but assumes that a satisfactory defence cannot be achieved along the lines of the existing debate between Minimalism and Contextualism. Rather, it is necessary to consistently distinguish two functional domains: the subjective processing domain and the interpersonal domain of communication, each with its own kind of utterance meaning. I will (...) argue that it is the mutually recognised content of the speaker's overt commitment that should be identified as ‘speaker meaning’. Diverging from the Gricean tradition, it is conventionally restricted, but genuinely pragmatic. Functional considerations show that it is, moreover, unnecessary to include further elements in ‘speaker meaning’. The distinction between two notions of utterance meaning with very different characteristics allows us to integrate the assumption of perfect sharing, which explains people's trust in communication, and the subjectivity of the hearer's inferences into a coherent and powerful model. (shrink)

The present paper addresses Aeschylus, and the way he wanted to be remembered by his fellow Athenians and the other Greeks. Having lived from 525/524 until 456/455 BCE, Aeschylus experienced the quick transition of his polis from a small city-state to a leading political and military force to be reckoned with throughout the Greek world. The inscription on his gravestone at Gela, Italy, commemorates his military achievements against the Persians, but makes no mention on his enormous theatrical renown. His plays (...) were so respected by the Athenians that after his death, his were the only tragedies allowed to be restaged in subsequent competitions. And yet Aeschylus, when time came to describe himself and the work of his lifetime, mentioned exclusively his contribution in the fight against the Persian Empire as an Athenian. Triggered by the poet’s narrative on his most memorable moment of his life, the present paper seeks to shed some light on the Athenian political identity, emerged during and soon after the Persian Wars, which not only derived from the newly-established democratic constitution of the late sixth century, but also supported it. Aeschylus’ epigram as well as some particular plays of his, narrates the confidence, the solidarity and the feeling of equality the Athenian citizens shared in regards to the defence of freedom of their polis as well as of all Greece, which came above anything else in their life, meaning above noble lineage and wealth. The gravestone of the poet stresses, in other words, how it felt like for an Athenian to live during the emergence of the very first Democracy that progressively supported the claim of Athens to become a ruler in the Aegean, by constructing its naval "Empire", ideologically upon the commemoration of the victory of the Athenian Democracy against the tyranny of Persia at Marathon and Salamis. (shrink)

This article considers the contribution that Jacques Derrida’s work Of Hospitality might make to higher music education as it unsettles the usual ascription of normative value to learning and teaching music at the university. Along these lines, what is most at issue in the encounter with Derrida’s thinking is the concomitant notion of forms of temporality—unpredictability, slowability, immeasurability, anticipation, serendipity, and surprise. Higher music education is seen as the practice of social transformation through the realization of the notion of unpredictability (...) of the “oral” being-together with and through music educational interactions that are not sacrificed to economically driven performance indicators and measurable outcomes. Furthermore, the article draws on the learning and teaching practices of de-familiarization of educational spaces and pedagogical responsibility to the others as ways to disrupt students’ fixed expectations about what good music teaching and mastery are. Overall, this article is a call to see unpredictability as another framework through which higher music education can seek to re-invent theoretical concepts as well as codes and conventions of teaching and learning practices by inviting us to contemplate their own insufficiency, incompleteness, and discontent. (shrink)

From the semiotics of theatrical representation to cultural anthropology or why theater (resists)? In this paper I propose an epistemological approach to the field of theatre semiotics from the beginning of the 20th century to our days. Firstly, I point out two different periods that have influenced theatre semiotics. The first one centres on reflections and studies by the Prague School of Structuralism. More precisely, I address Jan Mukařovsky’s essays about art and society as well as Jindrich Honzl’s contributions to (...) the study of sign and system in theatre. The second period presented here is that of theatre semiotics in the early 70s and late 80s in France.My goal here is to expose the main reasons that led theatre semiotics to a deadlock in the early 90s. Theatre semiotic research has been rich and fruitful in the beginning of last century. However, in our days it is generally deemed unadvisable to describe theatre representation in terms of sign and system.Although theatre semiotics used to be presented in French university classes, it is no longer possible to do so.Even though general semiotics has progressed by denying the importance of structure and by refusing to search for the minimal sign and its code, theatre semiotics has remained faithful to old communicational semiotics research.Throughout my contribution, I would like to examine the kind of semiotic field best fit to approaching an artistic domain such as theatre. In other words, I would like to show that Western theatre, granted it can be seen as a semiotic object, is first and foremost an artistic and cultural one.In order to do so, I propose a theoretical and methodological framework based on a specific semiotic model: the “indicial semiology” proposed by Anne-Marie Houdebine. Inspired by Juri Lotman’s essays about culture and art, I will try to set “indicial semiology” in the general field of a cultural anthropology. (shrink)

From the semiotics of theatrical representation to cultural anthropology or why theater (resists)? In this paper I propose an epistemological approach to the field of theatre semiotics from the beginning of the 20th century to our days. Firstly, I point out two different periods that have influenced theatre semiotics. The first one centres on reflections and studies by the Prague School of Structuralism. More precisely, I address Jan Mukařovsky’s essays about art and society as well as Jindrich Honzl’s contributions to (...) the study of sign and system in theatre. The second period presented here is that of theatre semiotics in the early 70s and late 80s in France.My goal here is to expose the main reasons that led theatre semiotics to a deadlock in the early 90s. Theatre semiotic research has been rich and fruitful in the beginning of last century. However, in our days it is generally deemed unadvisable to describe theatre representation in terms of sign and system.Although theatre semiotics used to be presented in French university classes, it is no longer possible to do so.Even though general semiotics has progressed by denying the importance of structure and by refusing to search for the minimal sign and its code, theatre semiotics has remained faithful to old communicational semiotics research.Throughout my contribution, I would like to examine the kind of semiotic field best fit to approaching an artistic domain such as theatre. In other words, I would like to show that Western theatre, granted it can be seen as a semiotic object, is first and foremost an artistic and cultural one.In order to do so, I propose a theoretical and methodological framework based on a specific semiotic model: the “indicial semiology” proposed by Anne-Marie Houdebine. Inspired by Juri Lotman’s essays about culture and art, I will try to set “indicial semiology” in the general field of a cultural anthropology. (shrink)

From the semiotics of theatrical representation to cultural anthropology or why theater (resists)? In this paper I propose an epistemological approach to the field of theatre semiotics from the beginning of the 20th century to our days. Firstly, I point out two different periods that have influenced theatre semiotics. The first one centres on reflections and studies by the Prague School of Structuralism. More precisely, I address Jan Mukařovsky’s essays about art and society as well as Jindrich Honzl’s contributions to (...) the study of sign and system in theatre. The second period presented here is that of theatre semiotics in the early 70s and late 80s in France.My goal here is to expose the main reasons that led theatre semiotics to a deadlock in the early 90s. Theatre semiotic research has been rich and fruitful in the beginning of last century. However, in our days it is generally deemed unadvisable to describe theatre representation in terms of sign and system.Although theatre semiotics used to be presented in French university classes, it is no longer possible to do so.Even though general semiotics has progressed by denying the importance of structure and by refusing to search for the minimal sign and its code, theatre semiotics has remained faithful to old communicational semiotics research.Throughout my contribution, I would like to examine the kind of semiotic field best fit to approaching an artistic domain such as theatre. In other words, I would like to show that Western theatre, granted it can be seen as a semiotic object, is first and foremost an artistic and cultural one.In order to do so, I propose a theoretical and methodological framework based on a specific semiotic model: the “indicial semiology” proposed by Anne-Marie Houdebine. Inspired by Juri Lotman’s essays about culture and art, I will try to set “indicial semiology” in the general field of a cultural anthropology. (shrink)

The paper focuses on the rivalry between philosophical excellence and Olympic prestige. Plato has philosophers quarrel not only with poets but also with Olympic victors. Epictetus will follow suit. Not sharing Plato's notion of philosophical excellence, Epictetus' Stoic sage rivals not only the Olympic athletes but classical philosophy itself.

The paper focuses on the rivalry between philosophical excellence and Olympic prestige. Plato has philosophers quarrel not only with poets but also with Olympic victors. Epictetus will follow suit. Not sharing Plato's notion of philosophical excellence, Epictetus' Stoic sage rivals not only the Olympic athletes but classical philosophy itself.

How chromatin bridges are detected by the abscission checkpoint during mammalian cell division is unknown. Here, we discuss recent findings from our lab showing that the DNA topoisomerase IIα (Top2α) enzyme binds to catenated (“knotted”) DNA next to the midbody and forms abortive Top2‐DNA cleavage complexes (Top2ccs) on chromatin bridges. Top2ccs are then processed by the proteasome to promote localization of the DNA damage sensor protein Rad17 to Top2‐generated double‐strand DNA ends on DNA knots. In turn, Rad17 promotes local recruitment (...) of the MRN protein complex and downstream ATM‐Chk2‐INCENP signaling to delay abscission and prevent chromatin bridge breakage in cytokinesis. (shrink)